Autophagy inhibition engages Nrf2-p62 Ub-associated signaling
نویسندگان
چکیده
منابع مشابه
p62 links autophagy and Nrf2 signaling.
The Nrf2-Keap1-ARE pathway is a redox and xenobiotic sensitive signaling axis that functions to protect cells against oxidative stress, environmental toxicants, and harmful chemicals through the induction of cytoprotective genes. To enforce strict regulation, cells invest a great deal of energy into the maintenance of the Nrf2 pathway to ensure rapid induction upon cellular insult and rapid ret...
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ژورنال
عنوان ژورنال: Autophagy
سال: 2011
ISSN: 1554-8627,1554-8635
DOI: 10.4161/auto.7.3.14780